Materials Science and Technology OverviewＥ：OM （旧：Overview５）

Materials Science and TechnologyOverviewＥ：Organic Materials （旧：Overview５）

998C105

秋山　好嗣

YOSHITSUGU AKIYAMA

2024年度後期

2024/second semester　

金曜1限

Fri. 8:50-10:20

先進工学研究科　マテリアル創成工学専攻

Department of Materials Science and Technology, Graduate School of Advanced Engineering

2.0単位

講義

Lecture

英語　English

① [対面]対面授業/ [On-site] On-site class

This lecture focus on design of highly functional organic molecules (1), as well as functional nanomaterials to understand the structural design methodologies (2).

1. Functional organic molecules, which can respond appropriately in various environments, are based on synthetic organic chemistry. The functional molecule with a low environmental load is a basic technology that supports the fields of environmental energy, pharmaceutical science, and chemical biology. In this lecture, we discuss outline regarding the concept of molecular design by synthetic organic chemistry, which is common to the methodologies of molecular design that play important roles in various fields. Our focus on rational design then shifts to the recent application of functional molecules.

2. Metal nanoparticles functionalized with DNA exhibit high stability under physiological salt conditions. The aggregated particles lead to induction of drastic color changes, due to a band shift of the surface plasmon resonance. Combining this phenomenon and the sophisticated molecular recognition ability of DNA can show great promise in a highly sensitive bioassays and molecular therapeutic applications. Also, recent progress in use of DNA-functionalized metal nanoparticles allows us to construct strictly controlled nanostructures formed with DNA origami-based nanotechnology, generating a significant impact in creating highly sophisticated nano-architectures. In this lecture, we discuss the preparation method and colloidal surface properties to understand the fundamental molecular design required for material engineering based on organic/inorganic hybrid nanomaterials.

The purpose of this lecture is to acquire the expertise and rational molecular design theory required for development of materials engineering. In particular, this lecture focus on highly functional organic molecules, as well as functional nanomaterials to understand the structural design methodologies.

For the above purposes, this lecture aims to
・ Acquire basic knowledge, ideas, and skills of retrosynthetic analysis that are indispensable for the creation of functional molecules.
・ Learn the methodologies based on the rational design of functional molecules.
・ Learn basic molecular design in various fields in an exercise format and deepen its contents.
・ Understand the theoretical structure and technical terms through the recent publication.
・ Improve your presentation and presentation skills so that your opinions and ideas can be communicated to others through presentations and discussions within faculty members and seminars.

リンク先の [評価項目と科目の対応一覧]から確認できます（学部対象）。
履修登録の際に参照ください。
​You can check this from “Correspondence table between grading items and subjects” by following the link(for departments).
https://www.tus.ac.jp/fd/ict_tusrubric/​​​

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課題に対する作文　Essay／小テストの実施　Quiz type test／ディベート・ディスカッション　Debate/Discussion／グループワーク　Group work／プレゼンテーション　Presentation

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(Preparation)
Graduate students need to summarize the points based on the materials distributed in the lecture (120min).
(Review)
Graduate students review the content of the lecture by several materials distributed in the lecture (120min).

This lecture will be evaluated comprehensively based on the exercises during the lecture and reports as well as the achievement assessment.

・S：到達目標を十分に達成し、極めて優秀な成果を収めている
・A：到達目標を十分に達成している
・B：到達目標を達成している
・C：到達目標を最低限達成している
・D：到達目標を達成していない
・-：学修成果の評価を判断する要件を欠格している

・S：Achieved outcomes, excellent result
・A：Achieved outcomes, good result
・B：Achieved outcomes
・C：Minimally achieved outcomes
・D：Did not achieve outcomes
・-：Failed to meet even the minimal requirements for evaluation

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教科書および一部の参考書は、MyKiTS (教科書販売サイト) から検索・購入可能です。
​https://mirai.kinokuniya.co.jp/tokyorika/​​​

It is possible to search for and purchase textbooks and certain reference materials at MyKiTS (online textbook store).
​​https://mirai.kinokuniya.co.jp/tokyorika/

For this lecture, material prints related to the contents of each lecture will be uploaded to LETUS.

1.　Chemical bonding and molecular interactions for organic materials
2.　Molecular structure of organic compounds
3.　Chemistry of organic materials 1: Material design
4.　Chemistry of organic materials 2: Organic reactions
5.　Disconnection approach for organic materials1: Hydroxy group
6.　Disconnection approach for organic materials2: Olefine cleavage
7.　Design of functional organic molecules1: Overviews
8.　Design of functional organic molecules2:Pharmaceutical approach
9.　Design of functional organic molecules3:Solid-phase synthesis
10.　Composite materials 1: DNA-based materials
11.　Composite materials 2: Nanocomposites
12.　Environmental and Social issues of organic materials 1: Biodegradable and self-immolative polymers
13.　Environmental and Social issues of organic materials 2: Atom economy
14.　Application of organic materials
15.　Summary and Achievement Evaluation

This Lecture will be given using the experience of researchers at overseas and domestic research institutions.

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